Progress in research and development in the medical field is always a good indicator. Hope is bestowed when such advances take place as they signal for better and new ways to deal with diseases. Among such progress is the advent of liposomal formulation in aiding in quicker and better ways of dealing with several ailments.
The formulation is a rightful step in the advancement of drugs. The procedure was discovered to curb the unwanted effects of drugs being exhausted before reaching the target areas. The initial phase of the process involves encapsulating the drug in a layer of digestible and healthy phospholipids. There were several options on the table, but after further research, liposomes were found to be the most favorable carriers.
The simplicity of the liposomes' structural composition is key to its performance. They are made up of an aqueous solution which is engulfed in a strengthened mesh of either natural or synthetic phospholipids. The advantage of this is that it can fuse non-reactively with both hydrophilic and hydrophobic drugs, each attaching to the element it does not react to.
Researchers have found the process of formation of these compounds may be critical to their performance. They are formed when strands of phospholipids are put in water, and a given heat amount is directed to them. The composition of the formed liposomes is tested against that of this drug it is intended to carry, so as to determine compatibility and avoid destructive reactions.
Advances like these have led to researchers getting further progress in the field. The most famous result being an anthracycline drug known as Doxorubicin, developed specifically to curb the spread of various variations of cancer. It inserts strains of base RNA and DNA into the malignant cells, and also the topoisomerase enzyme in later stages. This actively inhibits the spread of the disease.
It is due to advances in the medical field that control of many diseases is not a reality. Terminal illnesses previously viewed as a death sentence are now controllable and some even treatable. Research on cancer and liposomes has led to development of anti-cancer drugs an their carriers. The development has brought about continuing tests and usage of doxorubicin, paclitaxel, cisplatin, lipoplatin, aroplatin among others.
There has been considerable progress in the development of vaccines for diseases which do not have known cures. Such include hepatitis A, which now has a vaccine, Epaxal, under development. Inflexal V is a vaccine developed for several types of influenza especially in children. A vaccine for cancer known as Stimuvax is also in the offering.
Another point of progress thanks to this formulation has been in delivery of dietary supplements. It is still a new area under testing, but has great promise considering the level of success the formulations has garnered from targeted drug delivery. The process of the formulation is hence referred to as a new era of medical advances.
The formulation is a rightful step in the advancement of drugs. The procedure was discovered to curb the unwanted effects of drugs being exhausted before reaching the target areas. The initial phase of the process involves encapsulating the drug in a layer of digestible and healthy phospholipids. There were several options on the table, but after further research, liposomes were found to be the most favorable carriers.
The simplicity of the liposomes' structural composition is key to its performance. They are made up of an aqueous solution which is engulfed in a strengthened mesh of either natural or synthetic phospholipids. The advantage of this is that it can fuse non-reactively with both hydrophilic and hydrophobic drugs, each attaching to the element it does not react to.
Researchers have found the process of formation of these compounds may be critical to their performance. They are formed when strands of phospholipids are put in water, and a given heat amount is directed to them. The composition of the formed liposomes is tested against that of this drug it is intended to carry, so as to determine compatibility and avoid destructive reactions.
Advances like these have led to researchers getting further progress in the field. The most famous result being an anthracycline drug known as Doxorubicin, developed specifically to curb the spread of various variations of cancer. It inserts strains of base RNA and DNA into the malignant cells, and also the topoisomerase enzyme in later stages. This actively inhibits the spread of the disease.
It is due to advances in the medical field that control of many diseases is not a reality. Terminal illnesses previously viewed as a death sentence are now controllable and some even treatable. Research on cancer and liposomes has led to development of anti-cancer drugs an their carriers. The development has brought about continuing tests and usage of doxorubicin, paclitaxel, cisplatin, lipoplatin, aroplatin among others.
There has been considerable progress in the development of vaccines for diseases which do not have known cures. Such include hepatitis A, which now has a vaccine, Epaxal, under development. Inflexal V is a vaccine developed for several types of influenza especially in children. A vaccine for cancer known as Stimuvax is also in the offering.
Another point of progress thanks to this formulation has been in delivery of dietary supplements. It is still a new area under testing, but has great promise considering the level of success the formulations has garnered from targeted drug delivery. The process of the formulation is hence referred to as a new era of medical advances.
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